Viruses has published a review by Fedor Zurabov, Scientific Director at the Research and Production Center Micromir, titled “Bacteriophages as Phagobiotics: Scientific Rationale and Translational Boundaries for Gut Microbiome Modulation”.

The paper proposes phagobiotics as defined, purified, and process-controlled bacteriophages or phage cocktails intended for selective, non-therapeutic modulation of the gut microbiota. It distinguishes this concept from phage therapy and food biocontrol, reviews limited evidence on tolerability and selective microbial effects, and discusses quality control, genomic characterization, and product-specific evidence needs.

The review emphasizes that biological plausibility alone does not establish broad clinical efficacy. Further development would require product-specific, microbiome-aware studies, with future use framed proportionately to the available evidence.